- Saab, Elie
- Sade
- Sagebrecht, Marianne
- Saint, Eva Marie
- Saito, Takashi
- Salles, Walter
- Sambora, Richie
- Sanders, George
- Sanderson, William
- Sandler, Adam
- Saralegui, Cristina
- Sarandon, Chris
- Sarandon, Susan
- Sargent, Dick
- Satriani, Joe
- Savage, Ben
- Savage, Fred
- Savini, Tom
- Sawa, Devon
- Sayles, John
- Scacchi, Greta
- Scaggs, Boz
- Schell, Maximilian
- Schepisi, Fred
- Schiavelli, Vincent
- Schiffer, Claudia
- Schildkraut, Joseph
- Schlafly, Phyllis
- Schlesinger, John
- Schneider, Rob
- Schrader, Paul
- Schroeder, Barbet
- Schumacher, Joel
- Schwimmer, David
- Scioscia, Mike
- Scofield, John
- Scofield, Paul
- Scorsese, Martin
- Scott Thomas, Kristin
- Scott, George C.
- Scott, Ridley
- Scott, Tony
- Scully, Vin
- Seacrest, Ryan
- Seagal, Steven
- Secada, Jon
- Sedgwick, Kyra
- Seeger, Pete
- Segal, Peter
- Segel, Jason
- Seger, Bob
- Seinfeld, Jerry
- Selena
- Selleck, Tom
- Sellers, Peter
- Serrault, Michel
- Seth, Roshan
- Setzer, Brian
- Seuss, Dr.
- Sevigny, Chloe
- Sewell, Rufus
- Seymour, Jane
- Shaggy
- Shakira
- Shakur, Tupac
- Shandling, Garry
- Shankar, Ravi
- Shannon, Molly
- Shatner, William
- Shaver, Helen
- Shawn, Wallace
- Shean, Katee
- Shearer, Norma
- Sheen, Charlie
- Sheen, Martin
- Sheen, Michael
- Sheik, Duncan
- Shepard, Sam
- Shepherd, Cybill
- Shepherd, Kenny Wayne
- Sheridan, Ann
- Sherman, Vincent
- Shields, Brooke
- Shore, Pauly
- Short, Martin
- SHou, Robin
- Shriver, Maria
- Shue, Andrew
- Shue, Elisabeth
- Shyamalan, M. Night
- Siddig, Alexander
- Siddiqui, Aafia
- Siegel, Don
- Signoret, Simone
- Silverman, Sarah
- Silvers, Phil
- Silverstone, Alicia
- Sim, Alastair
- Simmons, Gene
- Simon, Carly
- Simon, David
- Simon, Paul
- Simpson, Ashlee
- Simpson, Bart
- Simpson, Jessica
- Simpson, Wallis
- Sinatra, Frank
- Sinatra, Nancy
- Sinese, Gary
- Singer, Bryan
- Singer, Marc
- Singleton, John
- Sinise, Gary
- Siriano, Christian
- Sirk, Douglas
- Siskel, Gene
- Sisqo
- Sizemore, Tom
- Skelton, Red
- Slater, Christian
- Slim, Fatboy
- Sloane, Eric
- Smashing Pumpkins
- Smith, Alexis
- Smith, Anna Nicole
- Smith, Elliott
- Smith, Harry
- Smith, Maggie
- Smith, Shawnee
- Smith, Will
- Smithson, Carly
- Smitrovich, Bill
- Smits, Jimmy
- Snipes, Wesley
- Snyder, Dana
- Sobule, Jill
- Soderbergh, Steven
- Soles, P.J.
- Solondz, Todd
- Sommers, Stephen
- Sondergaard, Gale
- Sonnenfeld, Barry
- Sorbo, Kevin
- Sorvino, Mira
- Sorvino, Paul
- Spacey, Kevin
- Spade, David
- Spader, James
- Sparks, Jordin
- Spears, Britney
- Spears, Jamie Lynn
- Spector, Phil
- Spelling, Tori
- Spheeris, Penelope
- Spice Girls
- Spielberg, Steven
- Spiner, Brent
- Spitzer, Silda Wall
- Spottiswoode, Roger
- Spradlin, G.D.
- Springer, Jerry
- Springfield, Rick
- Springsteen, Bruce
- Spurlock, Morgan
- Squier, Billy
- Stallone, Sly
- Stallone, Sylvester
- Stamos, John
- Stanton, Harry Dean
- Stanwyck, Barbara
- Stapleton, Maureen
- Starr, Ringo
- Steele, Barbara
- Steenburgen, Mary
- Stefani, Gwen
- Steiger, Rod
- Stein, Ben
- Sterling, Donald
- Stevens Jr., George
- Stevens, Cat
- Stevens, Stella
- Stevenson, Cynthia
- Stevenson, Juliet
- Stewart, James
- Stewart, Jimmy
- Stewart, Jon
- Stewart, Kristen
- Stewart, Martha
- Stewart, Patrick
- Stewart, Rod
- Stiller, Ben
- Sting
- Stockwell, Dean
- Stoltz, Eric
- Stone, Oliver
- Stone, Sharon
- Stowe, Madeleine
- Straight, Beatrice
- Strait, George
- Streep, Meryl
- Streisand, Barbra
- Styron, William
- Sugar Ray
- Sutherland, Donald
- Sutherland, Kiefer
- Suvari, Mena
- Swank, Hilary
- Swanson, Gloria
- Swanson, Kristy
- Swayze, Patrick
- Sweeney, D.B.
- Sweeney, Julia
- Sweet, Matthew
- Swift, Taylor
- Swinton, Tilda
- Swit, Loretta